NA
None
~ $9.00/day
Rectal Dosing500mg in 100mL Normal Saline q6h x 10 days (may use capsules or IV solution)
Severe/Complicated C. Diff Infection Dosing500mg PO/NG q6h x 10 days (along with metronidazole IV)
Taper Dosing125mg PO/NG QID x 7 days then
125mg PO/NG TID x 7 days then
125mg PO/NG BID x 7 days then
125mg PO/NG OD x 7days then
125mg PO/NG q2d x 7 days then
125mg PO/NG q3d x 7 days then stop
Usual Dosing125mg po/ng q6h for 10-14 days
Only indication is in the therapy of C. difficile infection, particularly recurrent or severe disease.
Possibility of accumulation in severe renal dysfunction.
Consider checking a vancomycin level in dialysis patients.
No oral absorption.
May increase vancomycin resistant Enterococci colonization in the gut.
Antimicrobial class: Glycopeptide
Pregnancy category: B
Average serum half life: 0 hours
Urine penetration: None
Lung penetration: None
CSF penetration: None
Biliary penetration: None
