Spectrum: Local Antimicrobial Stewardship, for Lake of the Woods District Hospital

Cefepime (Maxipime)

C. diff Risk

High

Oral Bioavailability

NA

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

General Spectrum of Activity

Antibiogram Data

Dosing

Adult

1-2g IV q8-12h

For serious pseudomonas infections use 2g IV q8h and consider extended interval dosing (infused over 3-4 hrs)

Renal

Not On Formulary

This medication is currently not on hospital formulary - please contact pharmacy if it is needed.

General Information

Common Usage

Common Usage

Broad spectrum antimicrobial with gram positive and gram negative coverage including Pseudomonas.

Used especially nosocomial infections involving resistant organisms.

Adverse Effects

Adverse Effects

  • Allergy (immediate & delayed)

  •  Positive Coombs

  •  Cytopenias

  •  Non-convulsive status epilepticus

Pharmacology

Pharmacology

Antimicrobial class: 4th generation Cephalosporin

Pregnancy category: B

Average serum half life: 2 hours

Biliary penetration: Moderate

CSF penetration: Therapeutic

Lung penetration: Therapeutic

Urine penetration: Therapeutic