Spectrum: Local Antimicrobial Stewardship, for Lake of the Woods District Hospital

Fidaxomicin (Dificid)

C. diff Risk

None

Oral Bioavailability

NA

Approximate Cost

~$200/day

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Adult

C. Difficile200mg po BID x 10days

Renal

No adjustment necessary - minimal systemic absorption.

Not On Formulary

This medication is currently not on hospital formulary - please contact pharmacy if it is needed.

General Information

Common Usage

Common Usage

C. difficile colitis

Adverse Effects

Adverse Effects

  •  GI disturbance

  •  Cytopenias

  •  Hypersensitivity: facial, tongue or throat swelling

Additional Information

Additional Information

Consult Pharmacy

Pharmacology

Pharmacology

Antimicrobial class: Specialized anti-C. difficile macrolide agent

Pregnancy category: B

Biliary penetration: None

CSF penetration: None

Lung penetration: None

Urine penetration: None