High
Excellent
PO ~ $1.50/day
IV ~ $14.00/day
Pneumonia including CAP, HAP, aspiration.
Some intra-abdominal infections.
CNS infections.
QTc prolongation
Dysglycemia
Rash
Tendinopathy and rupture
GI upset
Weakness exacerbation in myasthenia gravis
CNS toxicity including confusion, psychosis
QTc prolongation - Increased risk with other agents that prolong QTc
Divalent cations including Ca, Mg - Decreased absorption
Warfarin - Increased INR
Rifampin - Decrease moxifloxacin levels.
Antimicrobial class: Fluoroquinolone
Pregnancy category: C
Average serum half life: 12 hours
Urine penetration: Poor
Lung penetration: Therapeutic
CSF penetration: Therapeutic
Biliary penetration: Therapeutic
