Amoxicillin (Amoxil)

C. diff Risk

Low

Oral Bioavailability

Excellent

Approximate Cost

~$0.03/day

Spectrum Of Activity

Dosing

500-1000mg po TID

General Information

Common Usage

Therapy of Streptococcal and Enterococcal infections as well as susceptible gram negative infections.

Commonly used for upper respiratory infections and urinary tract infections.

Adverse Effects

  •  Allergy/rash (immediate or delayed)

  •  Note EBV related rash

  •  Cytopenias

Major Interactions

Allopurinol - increased rash

Pharmacology

Antimicrobial class: Aminopenicillin

Pregnancy category: B

Average serum half life: 1 hour

Urine penetration: Therapeutic

Lung penetration: Therapeutic

CSF penetration: Poor (except when meninges are inflamed)

Biliary penetration: Therapeutic