Community-acquired pneumonia
Bacteremia
Meningitis
Many other syndromes possible but uncommon including endocarditis, osteomyelitis, etc
The PCV-13 vaccine against 13 strains of S. pneumoniae is publically funded in Canada as part of the routine childhood immunization.
Invasive pneumococcal disease is a reportable disease
PCR testing from CSF is available if culture is negative and infection is still suspected. Please contact microbiology on call for this test.