Spectrum: Local Antimicrobial Stewardship, for CHEO-OCTC

Piperacillin

C. diff Risk

NA

Oral Bioavailability

NA

Approximate Cost

NA

Dosing

Pediatric

IV Dosing

Daily Dose: 200 - 300 mg/kg/day

Maximum Daily Dose: 24 g/day

Dosing Frequency: IV divided q6h

Neonatal

< 2 kg

  • 0 – 7 days: 150 mg/kg/day divided Q12H

  • &gt; 7 days: 225 mg/kg/day divided Q8H

> 2 kg

  • 0 – 7 days: 225 mg/kg/day divided Q8H

  • &gt; 7 days: 300 mg/kg/day divided Q6H