Spectrum: Local Antimicrobial Stewardship, for CHEO-OCTC

Doxycycline

C. diff Risk

Low

Oral Bioavailability

NA

Approximate Cost

$2-3/day (Oral)

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Pediatric

Daily Dose: 2 - 4 mg/kg/day

Maximum Daily Dose: 200 mg

Dosing Frequency: PO/IV divided BID or q12h

IV therapy is only available through the Special Access Programme of Health Canada

There is no age contraindication if therapy does not exceed 21 days.

General Information

First Line Indications

First Line Indications

Doxycycline is the optimal therapy for Lyme disease.

Oral Liquids

Oral Liquids

Concentration: 5 mg/mL (compounded)

Taste: Unpleasant taste

Not all strengths of oral liquids are listed nor be available on the CHEO Formulary

Tablet/Capsule Strengths

Tablet/Capsule Strengths
  • 100 mg

Tablets or capsules are preferred especially over an unpleasant tasting oral liquid.

Not all strengths of oral tablets/capsules are listed and they are not all available on the CHEO Formulary.