SAB Complicated vs. Uncomplicated

Endocarditis confirmed

Sustained bacteremia

Complications identified such as but not limited to septic arthritis, osteomyelitis, epidural/paraspinal abscess, intraabdominal abscess etc.

Patient has persistent fever despite 72hrs of effective antimicrobial therapy

Prosthetic material present. For example: central venous catheters, tunnelled lines, pacemakers, valves, graphs, prosthetic joints or other prosthetic material.

Source determined to be CVC.

CVC has been removed and repeat blood cultures are negative.

Active malignancy or immune supression