Female Uncomp Cystitis Rx

Directed Rx

Beta-lactams including cephalexin, cefuroxime, cefixime, amoxicillin, and amoxicillin-clavulanate may be used if susceptible but require 7d of therapy

Nitrofurantoin (5-7d, only if eGFR>60) and TMP-SMX (3d) are preferred agents when susceptible

Fluoroquinolone (3d) may be used for isolates with very limited susceptibility to other agents, but should be reserved for other uses

The microbiology lab can set up fosfomycin testing for organisms with limited susceptibility