Native Valve IE

Most Likely Pathogens

S. aureus - esp. IVDUs and nosocomial infection, acute

Viridans Streptococci - esp. community acquired, subacute

Enterococci

Less Common Pathogens

Coagulase negative Staphylococci

Culture negative

Other Streptococci

HACEK/CAKE - Cardiobacterium, Aggregatibacter, Eikenella, Kingella

Candida

Other gram negatives