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Antimicrobials
Change the catheter if present >2wks, and remove if not indicated
There is a high prevalence of asymptomatic bacteriuria and pyuria in nursing home patients, which does NOT require treatment (leads to resistance).
UTI should only be diagnosed and treated in symptomatic patients
For patients with nonspecific symptoms (falls, change in mental status) without signs of sepsis, improving hydration often resolves symptoms - suggest withholding ABx 24hrs and reassess
Review previous urine culture data if recurrent UTI (patient specific antibiogram) to better inform empiric choice
E. Coli isolates from Calgary nursing homes have reduced susceptibility to TMP-SMX (60%) and fluoroquinolones (50%), and higher prevalence of ESBLs
Ceftriaxone and gentamicin only cover 80% of nursing home E. coli in Calgary
IV: Piperacillin-Tazobactam 3.375 g IV q6h
OR
IV: Meropenem 500 g IV q6h